基本情况

尚庆利，教授，博士生导师

吉林大学唐敖庆学者-英才教授，入选吉林大学励新优秀青年教师培养计划（重点/精英）。目前主要从事昆虫毒理学与有害生物抗药性进化机制、农药生态毒理学与风险评估、农药新剂型研究。主持国家自然科学基金、吉林大学优秀青年教师培养计划等多项科研项目；在Insect Biochemistry and Molecular Biology、Journal of Agricultural and Food Chemistry、Pest Management Science等国际核心期刊上发表论文40多篇。参与Journal of Pest Science、Science of the Total Environment、Journal of Agricultural and Food Chemistry等30多个期刊及国家级人才和项目、捷克科学基金会（Grant Agency of the Czech Republic, GACR）、美国-以色列两国科学基金会（United States-Israel Binational Science Foundation, BSF）等项目通讯评审。

联系方式

电话：0431-87835596；

E-mail: shangqingli@163.com; shangqingli@jlu.edu.cn

通讯地址：吉林省长春市西安大路5333号，吉林大学和平校区5657威尼斯509室。

教育经历

2003/09–2008/07，中国农业大学，农学与生物技术学院，农业昆虫与害虫防治，博士；

1999/09–2003/07，山东农业大学，植物保护系，植物保护，学士；

工作经历

2016/09–至今，5657威尼斯，教授（破格）；

2012/09–2016/09，5657威尼斯，副教授；

2012/07–2012/09，5657威尼斯，讲师；

2010/01–2012/04，亚利桑那大学（美国），昆虫系，博士后；

主要兼职

中国昆虫学会药剂毒理专业委员会委员（2017年-今）

吉林省昆虫学会常务理事（2019年-今）

吉林大学青年科技工作者协会会员（2019年-今）

教学情况

本科生必修课程《昆虫研究法双语课》、《园艺植物昆虫学》

研究生选修课程《高级昆虫生理生化》

主要研究方向

昆虫毒理学与有害生物抗药性，农药生态毒理与风险评价

代表性课题

1.国家自然科学基金面上项目：螺虫乙酯抗性棉蚜ABC转运蛋白介导的杀虫药剂跨膜转运及表达调控机制，项目编号：32072457，起止时间：2021.01-2024.12。主持。

2.国家自然科学基金面上项目：LncRNA作为ceRNA靶向miRNA调控螺虫乙酯抗性棉蚜ACC过表达机制，项目编号：31772188，起止时间：2018.01-2021.12。主持。

3.国家自然科学基金青年基金：棉铃虫Transib转座子沉默相关piRNA克隆及其功能研究，项目编号：31301728，起止时间：2014.01-2016.12。主持。

4.国家自然科学基金面上项目：桃蚜CYP6CY3表达调控及其介导外源化合物协同进化研究，项目编号：31572024，起止时间：2016.01-2017.12。第一参加人。

5.国家自然科学基金青年基金：棉酚诱导棉蚜P450 CYP6A2表达调控机制研究，项目编号：31101456，起止时间：2012.01-2014.12。第一参加人。

6.吉林大学优秀青年教师培养计划(精英培养阶段)，起止时间：2019.04-2021.04。主持。

7.吉林大学优秀青年教师培养计划(重点培养阶段)，起止时间：2015.07-2018.07。主持。

8.国家公益性行业（农业）科研专项：二点委夜蛾、玉米螟等玉米重大害虫监测防控技术研究与示范—玉米螟绿色防控新技术及应急防治技术，项目编号：201303026-8，起止时间：2013.01-2017.12。子课题主持。

9.粮食丰产工程项目：粮食主产区主要病虫草害发生及其绿色防控关键技术-东北粳稻区主要病虫害的绿色防控技术，项目编号：2016YFD0300703，起止时间：2016.01-2020.12。参加。

论文[*通讯作者]

My ResearchGate：https://www.researchgate.net/profile/Qingli-Shang/research

1) Yuntong Lv, Jianyi Li, Kunpeng Yan, Yaping Ding, Xiwu Gao, Rui Bi, Hang Zhang, Yiou Pan*, Qingli Shang*. Functional characterization of ABC transporters mediates multiple-neonicotinoid resistance in a field population of Aphis gossypii Glover. Pesticide Biochemistry and Physiology. 2022. https://doi.org/10.1016/j.pestbp.2022.105264.

2) Yuntong Lv, Kunpeng Yan, Xiwu Gao, Xuewei Chen, Jianyi Li, Yaping Ding, Hang Zhang, Yiou Pan*, Qingli Shang*. Functional inquiry into ATP-Binding cassette transporter genes contributing to spirotetramat resistance in Aphis gossypii Glover. Journal of Agricultural and Food Chemistry. 2022. 70, 41, 13132-13142.

3) Yuntong Lv, Shuyun Wen, Yaping Ding, Xiwu Gao, Xuewei Chen, Kunpeng Yan, Fengting Yang, Yiou Pan*, Qingli Shang*. Functional validation of the roles of cytochrome P450s in tolerance to thiamethoxam and imidacloprid in a field population of Aphis gossypii. Journal of Agricultural and Food Chemistry. 2022. https://doi.org/10.1021/acs.jafc.2c04867.

4) Hongfei Xu, Kunpeng Yan, Yaping Ding, Yuntong Lv, Jianyi Li, Fengting Yang, Xuewei Chen, Xiwu Gao, Yiou Pan*, Qingli Shang*. Chemosensory proteins are associated with thiamethoxam and spirotetramat tolerance in Aphis gossypii Glover. International Journal of Molecular Sciences. 2022. 23(4), 2356.

5) Hongfei Xu, Yiou Pan, Jianyi Li, Fengting Yang, Xuewei Chen, Xiwu Gao, Shuyuan Wen, Qingli Shang*. Chemosensory proteins confer adaptation to the ryanoid anthranilic diamide insecticide cyantraniliprole in Aphis gossypii Glover. Pesticide Biochemistry and Physiology. 2022. 184, 105076.

6) Jianyi Li, Yuntong Lv, Kunpeng Yan, Fengting Yang, Xuewei Chen, Xiwu Gao, Shuyuan Wen, Hongfei Xu, Yiou Pan*, Qingli Shang*. Functional analysis of cyantraniliprole tolerance ability mediated by ATP-binding cassette transporters in Aphis gossypii Glover. Pesticide Biochemistry and Physiology. 2022. 184, 105104.

7) Tianfei Peng, Xuemei Liu, Fayi Tian, Hongfei Xu, Fengting Yang, Xuewei Chen, Xiwu Gao, Yuntong Lv, Jianyi Li, Yiou Pan*, Qingli Shang*. Functional investigation of lncRNAs and target cytochrome P450 genes related to spirotetramat resistance in Aphis gossypii Glover. Pest Management Science. 2022. 78: 1982-1991.

8) Tianfei Peng, Yiou Pan, Fayi Tian, Hongfei Xu, Fengting Yang, Xuewei Chen, Xiwu Gao, Jianyi Li, Haibao Wang, Qingli Shang*. Identification and the potential roles of long non-coding RNAs in regulating acetyl-CoA carboxylase ACC transcription in spirotetramat-resistant Aphis gossypii. Pesticide Biochemistry and Physiology. 2021. 179, 104972.

9) Zeng, Xiaochun; Pan, Yiou; Song, Jiaobao; Li, Jianyi; Lv, Yuntong; Gao, Xiwu; Peng, Tianfei; Tian, Fayi; Xu, Hongfei; Shang, Qingli*. Resistance risk assessment of the ryanoid anthranilic diamide insecticide cyantraniliprole in Aphis gossypii Glover. Journal of Agricultural and Food Chemistry. 2021. 69, 5849-5857.

10) Xiaochun Zeng, Yiou Pan, Fayi Tian, Jianyi Li, Hongfei Xu, Xuemei Liu, Xuewei Chen, Xiwu Gao, Tianfei Peng, Rui Bi, Qingli Shang*. Functional validation of key cytochrome P450 monooxygenase and UDP-glycosyltransferase genes conferring cyantraniliprole resistance in Aphis gossypii Glover. Pesticide Biochemistry and Physiology. 2021. 176, 104879.

11) Yiou Pan, Shuyuan Wen, Xuewei Chen, Xiwu Gao, Xiaochun Zeng, Xuemei Liu, Fayi Tian, Qingli Shang*. UDP-glycosyltransferases contribute to spirotetramat resistance in Aphis gossypii Glover. Pesticide Biochemistry and Physiology. 2020. 166: 104565.

12) Yiou Pan, Xiaochun Zeng, Shuyuan Wen, Xiwu Gao, Xuemei Liu, Fayi Tian, Qingli Shang*. Multiple ATP-binding cassette transporters genes are involved in thiamethoxam resistance in Aphis gossypii glover. Pesticide Biochemistry and Physiology. 2020. 167: 104558.

13) Yiou Pan, Xiaochun Zeng, Shuyuan Wen, Xuemei Liu, Qingli Shang*. Characterization of the Cap ‘n’ Collar Isoform C gene in Spodoptera frugiperda and its association with Superoxide Dismutase. Insects. 2020.11: 221.

14) Yiou Pan, Tianfei Peng, Pengjun Xu, Xiaochun Zeng, Fayi Tian, Jiabao Song, Qingli Shang*. Transcription Factors AhR/ARNT Regulate the expression of CYP6CY3 and CYP6CY4 switch conferring nicotine adaptation. International Journal of Molecular Sciences. 2019, 20(18):4521.

15) Yiou Pan, Pengjun Xu, Xiaochun Zeng, Xuemei Liu, Qingli Shang*. Characterization of UDP-glucuronosyltransferases and the potential contribution to nicotine tolerance in Myzus persicae. International Journal of Molecular Sciences. 2019, 20(15):3637.

16) Yongqiang Wu, Hongfei Xu, Yiou Pan, Xiwu Gao, Jinghui Xi, Juhong Zhang, Qingli Shang*. Expression profile changes of cytochrome P450 genes between thiamethoxam susceptible and resistant strains of Aphis gossypii Glover. Pesticide Biochemistry and Physiology. 2018. 149：1-7.

17) Yiou Pan, Pujin Chai, Chao Zheng, Hongfei Xu, Yongqiang Wu, Xiwu Gao, Jinghui Xi, Qingli Shang*. Contribution of cytochrome P450 monooxygenase CYP380C6 to spirotetramat resistance in Aphis gossypii Glover. Pesticide Biochemistry and Physiology. 2018. 148: 182-189.

18) Yiou Pan, Fayi Tian, Xiang Wei, Yongqiang Wu, Xiwu Gao, Jinghui Xi, Qingli Shang*. Thiamethoxam resistance in Aphis gossypii Glover relies on multiple UDP-glucuronosyltransferases. Frontier in Physiology. 2018. 9:322.

19) Tianfei Peng, Xuewei Chen, Yiou Pan, Chao Zheng, Xiang Wei, Jinghui Xi, Juhong Zhang, Xiwu Gao, Qingli Shang*. Transcription factor aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator is involved in regulation of the xenobiotic tolerance-related cytochrome P450 CYP6DA2 in Aphis gossypii Glover. Insect Molecular Biology. 2017. 26:485-495.

20) Xiang Wei, Yiou Pan, Xuecheng Xin, Chao Zheng, Xiwu Gao, Jinghui Xi, Qingli Shang*. Cross-resistance pattern and basis of resistance in a thiamethoxam-resistant strain of Aphis gossypii Glover. Pesticide Biochemistry and Physiology. 2017. 138:91-96.

21) Yiou Pan, E Zhu, Xiwu Gao, Ralf Nauen, Jinghui Xi, Tianfei Peng, Xiang Wei, Qingli Shang*. Novel mutations and expression changes of acetyl-CoA carboxylase are associated with spirotetramat resistance in Aphis gossypii Glover. Insect Molecular Biology. 2017. 26:383-391.

22) Xiang Wei, Chao Zheng, Tianfei Peng, Yiou Pan, Jinghui Xi, Xuewei Chen, Juhong Zhang, Shuang Yang, Xiwu Gao, Qingli Shang*. miR-276 and miR-3016-modulated expression of acetyl-CoA carboxylase accounts for spirotetramat resistance in Aphis gossypii Glover. Insect Biochemistry and Molecular Biology. 2016. 79:57-65.

23) Tianfei Peng, Yiou Pan, Xiwu Gao, Jinghui Xi, Lei Zhang, Kangsheng Ma, Yongqiang Wu, Juhong Zhang, Qingli Shang*. Reduced abundance of the CYP6CY3-targeting let-7 and miR-100 miRNAs accounts for host adaptation of Myzus persicae nicotianae. Insect Biochemistry and Molecular Biology. 2016. 75:89-97.

24) Tianfei Peng, Yiou Pan, Xiwu Gao, Jinghui Xi, Lei Zhang, Rui Bi, Chen Yang, Xuecheng Xin, Shuang Yang, Qingli Shang*. Cytochrome P450 CYP6DA2 regulated by CncC is associated with the gossypol tolerance in Aphis gossypii Glover. Insect Molecular Biology. 2016. 25: 450–459.

25) Tianfei Peng, Yiou Pan, Chen Yang, Xiwu Gao, Jinghui Xi, Yongqiang Wu, Xiao Huang, E Zhu, Xuecheng Xin, Chao Zhan, Qingli Shang*. Over-expression of CYP6A2 associated with spirotetramat resistance and cross resistance in the resistant strain of Aphis gossypii Glover. Pesticide Biochemistry and Physiology. 2016. 126: 64-69.

26) Juhong Zhang, Yiou Pan, Chao Zheng, Xiwu Gao, Xiang Wei, Jinghui Xi, Tianfei Peng, Qingli Shang*. Rapid evolution of symbiotic bacteria populations in spirotetramat resistant Aphis gossypii Glover revealed by Pyrosequencing. Comparative Biochemistry and Physiology, Part D. 2016. 20:151–158.

27) Qingli Shang, Yiou Pan, Tianfei Peng, Shuang Yang, Xin Lu, Zhenying Wang, Jinghui Xi. Proteomics analysis of over-expressed plasma proteins in response to cold acclimation in Ostrinia furnacalis. Archive of Insect Biochemistry and Physiology. 2015. 90: 195–200.

28) Y Pan, C Yang, X Gao, T Peng, R Bi, J Xi, X Xin, E Zhu, Y Wu, Q Shang*. Spirotetramat resistance adaption analysis of Aphis gossypii Glover by transcriptomic survey. Pesticide Biochemistry and Physiology. 2015. 124:73-80.

29) Pan Y, Peng T, Gao X, Zhang L, Yang C, Xi J, Xin X, Bi R, Shang Q*. Transcriptomic comparison of thiamethoxam-resistance adaptation in resistant and susceptible strains of Aphis gossypii Glover. Comparative Biochemistry and Physiology, Part D. 2015. 13:10-15.

30) Jinghui Xi, Yiou Pan, Zhenxin Wei, Chen Yang, Xiwu Gao, Tianfei Peng, Rui Bi, Yan Liu, Xuecheng Xin, Qingli Shang*. Proteomics-based identification and analysis proteins associated with spirotetramat tolerance in Aphis gossypii Glover. Pesticide Biochemistry and Physiology. 2015. 119:74-80.

31) Jinghui Xi, Yiou Pan, Rui Bi, Xiwu Gao, Xuewei Chen, Tianfei Peng, Min Zhang, Hua Zhang, Xiaoyue Hu, Qingli Shang*. Elevated expression of esterase and cytochrome P450 are related with lambda-cyhalothrin resistance and lead to cross resistance in Aphis glycines Matsumura. Pesticide Biochemistry and Physiology. 2015. 118: 77-81.

32) Qingli Shang*, Yiou Pan, Kui Fang, Jinghui Xi, Andrew Wong, James Andrew Brennan. Extensive Ace2 duplication and multiple mutations on Ace1 and Ace2 are related with high level of organophosphates resistance in Aphis gossypii. Environmental Toxicology. 2014. 29:526-533.

33) Qingli Shang*, Yiou Pan, Kui Fang, Jinghui Xi, James Andrew Brennan. Biochemical characterization of acetylcholinesterase, cytochrome P450 and cross-resistance in an omethoate-resistant strain of Aphis gossypii Glover. Crop Protection. 2012, 31, 15-20.

34) Yiou Pan, Qingli Shang, Kui Fang, Jing Zhang, Jinghui Xi. Down-regulated transcriptional level of Ace1 combined with mutations in Ace1 and Ace2 of Aphis gossypii are related with omethoate resistance. Chemical-Biological Interactions. 2010, 188: 553-557.

35) Qingli Shang, Pei Liang, Xiwu Gao. Cloning, developmental and tissue-specific expression of -aminobutyric acid (GABA) receptor alpha2 subunit gene from Spodoptera exigua (Hübner). Pesticide Biochemistry and Physiology. 2009, 93: 1-7.

36) Zhang L, Shang Q, Lu Y, Zhao Q, Gao X. A transferrin gene associated with development and 2-tridecanone tolerance in Helicoverpa armigera. Insect Molecular Biology. 2015. 24: 155–166.

37) Juanjuan Xin, Qingli Shang, Nicolas Desneux, Xiwu Gao. Genetic diversity of Sitobion avenae (Homoptera: Aphididae) populations from different geographic regions in China. PLoS One. 2014. 9(10): e109349.

38) Da Xiao, Yanhui Lu, Qingli Shang, Dunlun Song, Xiwu Gao. Gene silencing of two acetylcholinesterases reveals their cholinergic and non-cholinergic functions in Rhopalosiphum padi and Sitobion avenae. Pest Management Science. 2015. 71: 523–530.

39) Youhui Gong, Xinrui Yu, Qingli Shang, Xueyan Shi, Xiwu Gao. Oral delivery mediated RNA interference of a carboxylesterase gene results in reduced resistance to organophosphorus insecticides in the cotton aphid, Aphis gossypii Glover. PLoS One. 2014. 9(8): e102823.

40) Bi R, Pan Y, Shang Q, Peng T, Yang S, Wang S, Xin X, Liu Y, Xi J. Comparative proteomic analysis in Aphis glycines Mutsumura under lambda-cyhalothrin insecticide stress. Comparative Biochemistry and Physiology, Part D. 2016. 19:90-96.

41) Lei Zhang, Yao Lu, Min Xiang, Qingli Shang, Xiwu Gao. The retardant effect of 2-Tridecanone, mediated by Cytochrome P450, on the Development of Cotton bollworm, Helicoverpa armigera. BMC Genomics. 2016. 17:954.

42) Chuanwang Cao, Lili Sun, Rongrong Wen, Qingli Shang, Ling Ma, Zhiying Wang. Characterization of the transcriptome of the Asian gypsy moth Lymantria dispar identifies numerous transcripts associated with insecticide resistance. Pesticide Biochemistry and Physiology. 2015. 119:54-61.

43) Chen X, Xia J, Shang Q, Song D, Gao X. UDP-glucosyltransferases potentially contribute to imidacloprid resistance in Aphis gossypii Glover based on transcriptomic and proteomic analyses. Pesticide Biochemistry and Physiology. 2019. 159:98-106.

44) Tang F, Tu H, Shang Q, Gao X, Liang P. Molecular cloning, and characterization of five glutathione S-transferase genes and promoters from Micromelalopha troglodyta (Graeser) (Lepidoptera: Notodontidae) and their response to tannic acid stress. Insects. 2020, 11(6), 339.

专利：

1） 一种含螺虫乙酯和甲维盐的农药组合物，公开号：CN113785840A，公开日期：2021/12/14，申请号：CN202111086261.6。申请人：尚庆利、潘怡欧、刘雪梅、杨凤婷。

2） 一种含螺虫乙酯和氟啶虫酰胺的农药组合物，公开号：CN113812414A，公开日期：2021/12/14，申请号：CN202111087508.6。申请人：尚庆利、潘怡欧、刘雪梅、杨凤婷。